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CannaBiz Depot – A Leader in CBD Throughout the Nation

CBD You Can Trust

Our premium CBD, CBG, and hemp related products are designed to relieve many symptoms, whether it’s for you or your pets.

CannaBiz Depot – Available Nationwide with Headquarters in La Crosse, Wisconsin

CannaBiz Depot is your go-to shop for all things hemp and CBD. Our Cannabis Consultants greet you as you enter our modern, clean store. They will ask questions to learn more about your specific situation and work to earn your trust. We aim to build long-lasting relationships with our guests by providing honest and credible information about the hemp industry and the products we offer so you can make educated buying decisions based on your needs. 

Our staff and owners are dedicated to you! Whether you are looking to learn more about hemp and CBD or peruse our large selection of products, we have you covered when it comes to cannabis!

All of the hemp extract/CBD products that we sell at CannaBiz Depot have been 3rd party lab tested and contain less than 0.3% THC.

Check Out Our Special Offers

Your One-Stop Shop for Premium Hemp Products

CannaBiz Depot offers a vast selection of quality hemp, CBD, and CBG products This includes clothing & accessories, bath & beauty products, pet care products, body care products, and more.   

Bath & Beauty


Delta 8


Food & Beverages



Clothing & Accessories

Stop By Our Stores & Say Hello!

CannaBiz Depot’s original retail store is located on 4th and Pearl Street in Historic Downtown La Crosse, Wisconsin right in the heart of God’s County. Our beautiful and vibrant downtown is a center for arts, entertainment, award-winning restaurants, taverns, live music, museums, hotels, and now hemp & CBD retail.

Visitors can enjoy the scenic beauty of the Mississippi River, take a riverboat cruise, stroll through our beautiful parks & trails, and soak up the historic storefronts.

We are very proud to be in headquartered in La Crosse, Wisconsin and the community in which we work and live and we want to show it off to you!

Front desk with customers at Cannabiz Depot in La Crosse, Wisconsin.

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