CannaBiz Depot in La Crosse, WI.

CBD You Can Trust.

Our premium CBD and hemp products are designed to relieve many symptoms, whether it’s for you or your pets.

CannaBiz Depot in La Crosse

CannaBiz Depot, located in La Crosse, WI is your go-to shop for all things hemp and CBD. Our cannabis consultants greet you as you enter our modern, clean, and beautifully remodeled store. They will ask questions to learn more about your specific situation and work to earn your trust. We aim to build long lasting relationships with our guests by providing honest and credible information about the hemp industry so you can make educated buying decisions based on your needs. 

Our staff and owners are dedicated to you! Whether you are looking to learn more about hemp and CBD, peruse through our products, we have you covered when it comes to cannabis!

All of the hemp extract/CBD products that we sell at CannaBiz Depot have been 3rd party lab tested and contain less than 0.3% THC.

Check Out Our Special Offers

  • 1-cbd-hemp-hour-discount
  • 2-cbd-medible-monday-discount
  • cbd-topical-tuesday-discount
  • cbd-hemp-wednesday-discount
  • 5-cbd-therapeutic-thursday-discount
  • 6-cbd-flower-friday-discount
  • 7-cbd-swag-saturday-discount
  • 8-cbd-pet-sunday-discount
  • 9-cbd-veterans-discount
  • 10-cbd-happy-birthday-discount

Your One-Stop Shop for Premium Hemp Products

At CannaBiz Depot, we offer a vast selection of hemp extract CBD products, clothing & accessories, bath & beauty products, pet care products, and more. 

Bath & Beauty


Food & Beverages

Stop By Our Store & Say Hello!

CannaBiz Depot is located on 4th and Pearl Street in Historic Downtown La Crosse, right in the heart of God’s County. Our beautiful, and vibrant, downtown is a center for arts, entertainment, award-winning restaurants, taverns, live music, museums, hotels, and now hemp & CBD retail.

Visitors can enjoy the scenic beauty of the Mississippi River, take a riverboat cruise, stroll through our beautiful parks & trails, and soak up the historic storefronts.

We are very proud to be in La Crosse, WI and the community in which we work and live and we want to show it off to you!

CannaBiz Depot's sales counter surrounded by customers.

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