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CannaBiz Depot – A Nationwide Leader in CBD

Front desk with customers at Cannabiz Depot in La Crosse, Wisconsin.

Headquartered in La Crosse, WI – Franchises Available Nationwide

CannaBiz Depot is a locally-owned, cannabis retail outlet that opened its first location at 200 4th St. S La Crosse, WI 54601. Everything in our stores is related to the cannabis plant. This includes our food & beverages, clothing & accessories, bath & beauty line, health & wellness products, pet products, and much more.

We offer a huge selection of high quality, 3rd party lab tested, organic CBD and CBG at the most affordable prices in the industry. Our most popular brand of CBD is our own CannaBiz Depot label.  In addition, we also offer some of the most well-known hemp brands in the industry on our shelves.  We will help you find a product that suites your needs and it will be at a great price.

Our Vision

The CannaBiz Depot mission is to be a customer-driven, community-focused, industry leader in the hemp retail market. We take pride in the quality of products that we offer and prices we sell them at. We feel that high-quality CBD and hemp products should be affordable to everyone. We are passionate about cannabis!

Manager Marcus Trevakis and owner Matt Boshcka holding donation check for school lunch debt.

Community Focused

We are always looking for ways to give back to the community. Which is why we partnered up with Beer by Bike Brigade to help pay off school lunch debt by donating 10% of our sales from CBD food and drink purchases. Check out the story here.

Our plan is to continue to give back to the community in a variety of ways including causes like animal rescue, mental health, addiction, and poverty.


We love our customers, especially loyal ones. To show our appreciation, we created a loyalty program with the following CBDeece perks:

  • $5 off chip with a purchase of $75+
  • Spin the CBDeal of Fortune and have a chance to win a discount or free product with a purchase of $75+
  • $5 credit after you earn 100pts (1pt = $1 spent)
  • Birthday gifts – 1 free pre-roll the day of your birthday, and 25% off 1 purchase during your birthday week
  • Monthly store e-mail
  • Social media giveaways
  • Daily deals
  • Opportunities to win free swag on a daily basis

Plus, all customers who purchase a $25 gift card will receive a $5 chip.